Submit Manuscript  

Article Details

Applications of Solid-State Fermentation Process in Biological Detoxification of Industrial Wastes

[ Vol. 1 , Issue. 1 ]


Chetna Joshi, Sunil K. Khare and Munishwar N. Gupta   Pages 35 - 49 ( 15 )


Solid–state fermentation (SSF) has been a useful technique for utilization of large volumes of agro-industrial biomass in producing value added enzymes and platform chemicals. Herein, the microorganisms are grown on complex biomass as substrate. They draw the nutrients from biomass and in turn generate the useful metabolites and enzymes. In recent past SSF has been observed to be a versatile technique for simultaneous detoxification of ‘toxins or antinutrients’ present in the biomass. SSF based detoxification of agro-industrial wastes has been established in case of; phorbol esters (in jatropha seed cake), ricin (in castor bean cake), caffeine (in coffee husk), gossypol (in cotton seed meal) and glucosinolates (in rapeseed meal) etc. Furthermore, some notable examples have emerged on xenobiotics and dye degradation through this approach. Present review looks at these detoxification studies and their mechanistic aspects, potential applications and further challenges in the area.


Agro-industrial waste, biodetoxification, bioremediation, dye degradation, plant toxins, solid-state fermentation, jatropha seed cake.


Enzyme and Microbial Biochemistry Lab, Department of Chemistry, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi 110016 India.

Read Full-Text article